Publications

2018

Segal, D., Zaritsky, A., Schejter, E.D. and Shilo, B-Z.

Feedback inhibition of action on Rho mediates content release from large secretory vesicles. Journal of Cell Biology, doi: 10.1083/jcb.201711006 (2018)

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2017

Shilo, B-Z. and Sprinzak, D.

The lipid-binding side of Notch ligands. EMBO J. 36, 2182-2183 (2017).

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Shilo, B-Z. and Barkai, N.

Buffering global variability of morphogen gradients. Developmental Cell 40, 429-438 (2017).

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Shilo, B-Z. and Barkai, N.

Lighting up ERK activity. Developmental Cell 40, 115-116 (2017).

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2016

The Drosophila formin Fhos is a primary mediator of sarcomeric thin-filament array assembly

Shwartz, A., Dhanyasi, N., Schejter, E.D. and Shilo, B-Z. eLife 5:e1654 (2016).

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Adhesion and Fusion of Muscle Cells Are Promoted by Filopodia

Segal, D., Dhanyasi, N., Schejter, E.D. and Shilo, B-Z. Developmental Cell 38, 291-304 (2016).

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Developmental roles of Rhomboid proteases

Shilo, B-Z. Seminars in Cell and Developmental Biology, in press (2016).

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New twists in Drosophila cell signaling

Shilo, B-Z. J Biol Chem 291, 7805-7808 (2016).

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A WntD-Dependent Integral Feedback Loop Attenuates Variability in Drosophila Toll Signaling

Rahimi, N., Averbukh, I., Haskel-Ittah., M., Degani, N., Schejter, E., Barkai, N., and Shilo, B-Z. Developmental Cell 36, 401-414 (2016).

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Periodic patterning of the Drosophila eye is stabilized by the diffusible activator Scabrous

Gavish, A., Shwartz, A., Weizman, A., Schejter, E., Shilo, B-Z. and Barkai, N. Nature communications 10461 (2016).

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2015

Orchestrated content release from Drosophila glue-protein vesicles by a contractile actomyosin network

Rousso, T., Schejter, E.D. and Shilo, BZ.
Nat Cell Biol. 18, 181-190 (2016).

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News and Views

Nature Cell Biology 18, 142-144 (2016)

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Surface apposition and multiple cell contacts promote myoblast fusion in Drosophila flight muscles

Nagaraju Dhanyasi, Dagan Segal, Eyal Shimoni, Vera Shinder, Ben‑Zion Shilo, K. VijayRaghavan, and Eyal D. Schejter
Journal of Cell Biology 211, 191-203 (2015).

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Surface apposition and multiple cell contacts promote myoblast fusion in Drosophila flight muscles

October 12 issue cover.

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The Edges of Pancreatic Islet Beta Cells Constitute Adhesive and Signaling Microdomains.

Geron E, Boura-Halfon S, Schejter ED, Shilo BZ.

Cell Reports,  pii: S2211-1247(14)01060-2 (2015).

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The Edges of Pancreatic Islet Beta Cells Constitute Adhesive and Signaling Microdomains.

January 20 issue cover.

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2014

Life's Blueprint: The science and art of embryo creation.

Shilo BZ.

Yale University Press (New Haven & London).

http://shilobook.weizmann.ac.il/

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The regulation and functions of MAPK pathways in Drosophila.

Shilo BZ.

Methods, 68: 151-159.

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Assessing the secretory capacity of pancreatic acinar cells.

Geron E, Schejter ED, Shilo BZ.

J. Vis. Exp. (90), e51799, doi:10.3791/51799.

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N-wasp is required for structural integrity of the blood-testis barrier.

Xiao X, Mruk DD, Tang EI, Massarwa R, Mok KW, Li N, Wong CK, Lee WM, Snapper SB, Shilo BZ, Schejter ED, Cheng CY.

PLoS Genet., 10:e1004447.

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Scaling of dorsal-ventral patterning in the Xenopus laevis embryo.

Ben-Zvi D, Fainsod A, Shilo BZ, Barkai N.

Bioessays, 36:151-156.

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2013

Conveying principles of embryonic development by metaphors from daily life.

Shilo BZ.

Development, 140:4827-4829.

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Apical targeting of the formin Diaphanous in Drosophila tubular epithelia.

Rousso T, Shewan AM, Mostov KE, Schejter ED, Shilo BZ.

eLife, 2:e00666.

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Sequential activation of ETS proteins provides a sustained transcriptional response to EGFR Signaling.

Shwartz A, Yogev S, Schejter ED, Shilo BZ.J

Development, 140:2746-2754.

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Directing exocrine secretory vesicles to the apical membrane by actin cables generated by the formin mDia1.

Creating gradients by morphogen shuttling.

Shilo BZ, Haskel-Ittah M, Ben-Zvi D, Schejter ED, Barkai N.

Trends Genet., 29:339-347.

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Segmentation within scale.

Barkai N, Shilo B.
Nature, 493:32-34.

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2012

Bidirectional Notch activation represses fusion competence in swarming adult Drosophila myoblasts .

Gildor B, Schejter ED, Shilo B-Z.

Development, 139:4040-4050.

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Orienting the direction of EGFR activation.

Dev Cell., 23:449-450.

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Self-organized shuttling: generating sharp dorsoventral polarity in the early Drosophila embryo.

Haskel-Ittah M, Ben-Zvi D, Branski-Arieli M, Schejter ED, Shilo BZ, Barkai N.

Cell, 150:1016-1028.

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Signaling mechanisms controlling cell fate and embryonic patterning.

Perrimon N, Pitsouli C, Shilo BZ.

Cold Spring Harb Perspect Biol., 4:a005975.

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The actin regulator N-WASp is required for muscle-cell fusion in mice.

Gruenbaum-Cohen Y, Harel I, Umansky KB, Tzahor E, Snapper SB, Shilo BZ, Schejter ED.

Proc Natl Acad Sci U S A, 109:11211-11216.

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2011

Regulation of developmental intercellular signalling by intracellular trafficking.

Shilo BZ, Schejter ED.

EMBO J., 30:3516-3526.

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Scaling of morphogen gradients.

Ben-Zvi D, Shilo BZ, Barkai N.

Curr Opin Genet Dev., 21:704-710.

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Expansion-repression mechanism for scaling the Dpp activation gradient in Drosophila wing imaginal discs.

Ben-Zvi D, Pyrowolakis G, Barkai N, Shilo BZ.

Curr Biol., 21:1391-1396.

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The Wasp-based actin polymerization machinery is required in somatic support cells for spermatid maturation and release.

Rotkopf S, Hamberg Y, Aigaki T, Snapper SB, Shilo BZ, Schejter ED.

Development, 138:2729-2739.

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The actin nucleator WASp is required for myoblast fusion during adult Drosophila myogenesis.

Mukherjee P, Gildor B, Shilo BZ, VijayRaghavan K, Schejter ED.

Development, 138:2347-2357.

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Versatility of EGF receptor ligand processing in insects.

Yogev S, Rousso T, Schejter ED, Shilo BZ.

Dev Biol., 357:17-20.

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2010

Polarized secretion of Drosophila EGFR ligand from photoreceptor neurons is controlled by ER localization of the ligand-processing machinery.

Yogev S, Schejter ED, Shilo BZ.

PLoS Biol., 28: pii: e1000505.

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Insider influence on ErbB activity.

Shilo BZ.

Cell, 143:181-182.

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Generation of distinct signaling modes via diversification of the Egfr ligand-processing cassette.

Rousso T, Lynch J, Yogev S, Roth S, Schejter ED, Shilo BZ.

Development, 137:3427-3437.

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The numbers behind morphogenesis.

Shilo BZ.

EMBO Rep., 11:243-5.

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Making muscles: Arp, two, three.

Gildor B, Massarwa R, Shilo BZ, Schejter ED.

Fly, 4:145-148.

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2009

Robust generation and decoding of morphogen gradients.

Barkai N, Shilo BZ.

Cold Spring Harb Perspect Biol., 1:a001990.

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The SCAR and WASp nucleation-promoting factors act sequentially to mediate Drosophila myoblast fusion.

Gildor B, Massarwa R, Shilo BZ, Schejter ED.

EMBO Rep., 10:1043-1050.

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Apical secretion in epithelial tubes of the Drosophila embryo is directed by the Formin-family protein Diaphanous.

Massarwa R, Schejter ED, Shilo BZ.

Dev Cell. 16:877-888.

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Phyllopod at the intersection of developmental signalling pathways.

Shilo BZ.

EMBO J., 28:311-312.

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2008

Scaling of the BMP activation gradient in Xenopus embryos.

Ben-Zvi D, Shilo BZ, Fainsod A, Barkai N.

Nature, 453:1205-12011.

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Drosophila EGFR signalling is modulated by differential compartmentalization of Rhomboid intramembrane proteases.

Yogev S, Schejter ED, Shilo BZ.

EMBO J., 27:1219-1230.

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Re-examining the stability of the Bicoid morphogen gradient.

Bergmann S, Tamari Z, Schejter E, Shilo BZ, Barkai N.

Cell, 132:15-17

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